In order to investigate the mechanisms relevant to the development of therapy-resistant tumours, we established a new tumour model which closely resembles the situation in patients who receive androgen ablation therapy.
Detection of EBV infection at the single-cell level. Precise quantitation of virus-infected cells in vivo. Detection and discrimination of latent and replicative herpesvirus infection at Tanner sutkowski single cell level in vivo. Cells expressing the Epstein-Barr virus growth program are present in and Tanner sutkowski to the naive B-cell subset of healthy tonsils.
Tonsillar memory B cells, latently infected with Epstein-Barr virus, express the restricted pattern of latent genes previously found only in Epstein-Barr virus-associated tumors.
EBV persistence involves strict selection of latently infected B cells. Epstein-barr virus-infected resting memory B cells, not proliferating lymphoblasts, accumulate in the peripheral blood of immunosuppressed patients.
A model for persistent infection with Epstein-Barr virus: CD48 binds to heparan sulfate on the surface of epithelial cells. EBV persistence in memory B cells in vivo. A ligand for human CD48 on epithelial cells.
J Neuropathol Exp Neurol. Epstein-Barr virus latent membrane protein does not inhibit differentiation and induces tumorigenicity of human epithelial cells. Identification of the site of Epstein-Barr virus persistence in vivo as a resting B cell.
An Epstein-Barr virus-associated superantigen. Is EBV persistence in vivo a model for B cell homeostasis? The Kaposi sarcoma-associated herpesvirus KSHV is present as an intact latent genome in KS tissue but replicates in the peripheral blood mononuclear cells of KS patients.
Detection of the latent form of Epstein-Barr virus DNA in the peripheral blood of healthy individuals. Epstein-Barr virus and the B cell: The interplay of herpesviruses in AIDS: A novel form of Epstein-Barr virus latency in normal B cells in vivo.
Characterization of the CD48 gene demonstrates a positive element that is specific to Epstein-Barr virus-immortalized B-cell lines and contains an essential NF-kappa B site. A new form of Epstein-Barr virus latency in vivo.
Curr Top Microbiol Immunol.
Function of CD48 and its regulation by Epstein-Barr virus. Biochemical, genetic, and functional analyses of the phosphorylation sites on the Epstein-Barr virus-encoded oncogenic latent membrane protein LMP All three domains of the Epstein-Barr virus-encoded latent membrane protein LMP-1 are required for transformation of rat-1 fibroblasts.
Is there a unique episome in EBV transformed B cells? The prototypical Epstein-Barr virus-transformed lymphoblastoid cell line IB4 is an unusual variant containing integrated but no episomal viral DNA. When Epstein-Barr virus persistently infects B-cell lines, it frequently integrates.
Characterization of genomic polymorphism of an activation-associated antigen, Blast Genomic integration as a novel mechanism of EBV persistence. Immunological responses to Epstein-Barr virus infection and the pathogenesis of EBV-induced diseases.Tanner Sutkowski in the United States We found 1 people in the US matching Tanner Sutkowski.
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Tanner Sutkowski of Scarborough, ME, will attend the University of Dayton this fall as part of an incoming class that is the most selective in .
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jordan Sutkowski. AS Autumn Sutton. DS Danielle Swankoski Arena Tanner. PT Penny Tanner . William Stembuig, Jean Sutkowski James Sweeney, Elizabeth Talamo. Suzanne Tanner. Ronald Tesoneio, Robert Tonkin Nancy Turner, Pat "VonEsch, James Wilson, Jane Wilson.
Based in Westbury, NY, New York Community Bancorp, Inc. is a leading producer of multi-family loans on non-luxury, rent-regulated apartment buildings in New York City, and the parent of New York Community Bank and New York Commercial Bank.